TY - JOUR
T1 - Thoracotomy as a Staging Procedure after Chemotherapy in the Treatment of Stage III Nonseminomatous Carcinoma of the Testis
AU - Prenger, K.
AU - Eysman, L.
AU - van der Heide, J. N.Homan
AU - Oldhoff, J.
AU - Sleijfer, D. Th
AU - Koops, H. Schraffordt
AU - Oosterhuis, J. W.
PY - 1984
Y1 - 1984
N2 - Of 108 patients with a nonseminomatous testicular carcinoma, 28 with lung metastases were studied. After combination chemotherapy with cisplatin, vinblastine, and bleomycin (PVB), 11 patients underwent exploratory thoracotomy. Viable carcinomatous tissue, along with fibrosis, necrosis, and mature teratoma, was found in 4 patients. Three of these patients were successfully retreated with VP 16-213, cisplatin, and actinomycin D. In patients with residual pulmonary or mediastinal masses after chemotherapy, resection of the lesions is mandatory to demonstrate viable carcinoma so that treatment can be readministered. Thus, in our view, thoracotomy is a diagnostic procedure.
AB - Of 108 patients with a nonseminomatous testicular carcinoma, 28 with lung metastases were studied. After combination chemotherapy with cisplatin, vinblastine, and bleomycin (PVB), 11 patients underwent exploratory thoracotomy. Viable carcinomatous tissue, along with fibrosis, necrosis, and mature teratoma, was found in 4 patients. Three of these patients were successfully retreated with VP 16-213, cisplatin, and actinomycin D. In patients with residual pulmonary or mediastinal masses after chemotherapy, resection of the lesions is mandatory to demonstrate viable carcinoma so that treatment can be readministered. Thus, in our view, thoracotomy is a diagnostic procedure.
UR - http://www.scopus.com/inward/record.url?scp=0021681978&partnerID=8YFLogxK
U2 - 10.1016/S0003-4975(10)64182-3
DO - 10.1016/S0003-4975(10)64182-3
M3 - Article
AN - SCOPUS:0021681978
SN - 0003-4975
VL - 38
SP - 444
EP - 446
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 5
ER -