Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo

Mark Kerstjens; Sandra S. Pinhancos; Patricia Garrido Castro; Pauline Schneider; Priscilla Wander; Rob Pieters; Ronald W. Stam

doi:10.3324/haematol.2017.174060

Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo

Mark Kerstjens
, Sandra S. Pinhancos
, Patricia Garrido Castro
, Pauline Schneider
, Priscilla Wander
, Rob Pieters
, Ronald W. Stam

Research output: Contribution to journal › Letter › peer-review

31 Citations (Scopus)

Original language	English
Pages (from-to)	e147-e150
Journal	Haematologica
Volume	103
Issue number	4
DOIs	https://doi.org/10.3324/haematol.2017.174060
Publication status	Published - 23 Mar 2018

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10.3324/haematol.2017.174060

Cite this

@article{64dcbb909d344dab94cecb4dd6372e39,

title = "Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo",

author = "Mark Kerstjens and Pinhancos, \{Sandra S.\} and Castro, \{Patricia Garrido\} and Pauline Schneider and Priscilla Wander and Rob Pieters and Stam, \{Ronald W.\}",

year = "2018",

month = mar,

day = "23",

doi = "10.3324/haematol.2017.174060",

language = "English",

volume = "103",

pages = "e147--e150",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

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TY - JOUR

T1 - Trametinib inhibits RAS-mutant MLL-rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo

AU - Kerstjens, Mark

AU - Pinhancos, Sandra S.

AU - Castro, Patricia Garrido

AU - Schneider, Pauline

AU - Wander, Priscilla

AU - Pieters, Rob

AU - Stam, Ronald W.

PY - 2018/3/23

Y1 - 2018/3/23

UR - https://www.scopus.com/pages/publications/85044403063

U2 - 10.3324/haematol.2017.174060

DO - 10.3324/haematol.2017.174060

M3 - Letter

C2 - 29419436

AN - SCOPUS:85044403063

SN - 0390-6078

VL - 103

SP - e147-e150

JO - Haematologica

JF - Haematologica

IS - 4

ER -