TuBaFrost 6: Virtual microscopy in virtual tumour banking

I. Teodorovic, M. Isabelle, A. Carbone, A. Passioukov, S. Lejeune, D. Jaminé, P. Therasse, A. Gloghini, W. N.M. Dinjens, K. H. Lam, M. H.A. Oomen, A. Spatz, C. Ratcliffe, K. Knox, R. Mager, D. Kerr, F. Pezzella, B. van Damme, M. van de Vijver, H. van BovenM. M. Morente, S. Alonso, D. Kerjaschki, J. Pammer, J. A. Lopez-Guerrero, A. Llombart Bosch, E. B. van Veen, J. W. Oosterhuis, P. H.J. Riegman

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)


Many systems have already been designed and successfully used for sharing histology images over large distances, without transfer of the original glass slides. Rapid evolution was seen when digital images could be transferred over the Internet. Nowadays, sophisticated Virtual Microscope systems can be acquired, with the capability to quickly scan large batches of glass slides at high magnification and compress and store the large images on disc, which subsequently can be consulted through the Internet. The images are stored on an image server, which can give simple, easy to transfer pictures to the user specifying a certain magnification on any position in the scan. This offers new opportunities in histology review, overcoming the necessity of the dynamic telepathology systems to have compatible software systems and microscopes and in addition, an adequate connection of sufficient bandwidth. Consulting the images now only requires an Internet connection and a computer with a high quality monitor. A system of complete pathology review supporting bio-repositories is described, based on the implementation of this technique in the European Human Frozen Tumor Tissue Bank (TuBaFrost).

Original languageEnglish
Pages (from-to)3110-3116
Number of pages7
JournalEuropean Journal of Cancer
Issue number18
Publication statusPublished - Dec 2006
Externally publishedYes


  • Virtual bio-repository
  • Virtual microscope
  • Virtual tissue banking
  • Virtual tumour bank


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