Tyrosine kinase inhibitor levels matter in treating chronic GVHD

Lotte van der Wagen; Julie Janssen; Reinier Raijmakers; Eefke Petersen; Moniek de Witte; Niels de Jong; Mar Bellido; Ellen Meijer; Brigitte Bär; Jaap Jan Boelens; Alwin Huitema; Jürgen Kuball

doi:10.1038/s41409-018-0429-5

Tyrosine kinase inhibitor levels matter in treating chronic GVHD

Lotte van der Wagen
, Julie Janssen
, Reinier Raijmakers
, Eefke Petersen
, Moniek de Witte
, Niels de Jong
, Mar Bellido
, Ellen Meijer
, Brigitte Bär
, Jaap Jan Boelens
, Alwin Huitema
, Jürgen Kuball

Research output: Contribution to journal › Letter › peer-review

1 Citation (Scopus)

Abstract

We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease.These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.

Original language	English
Pages (from-to)	1141-1144
Number of pages	4
Journal	Bone Marrow Transplantation
Volume	54
Issue number	7
DOIs	https://doi.org/10.1038/s41409-018-0429-5
Publication status	Published - 1 Jul 2019
Externally published	Yes

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10.1038/s41409-018-0429-5

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title = "Tyrosine kinase inhibitor levels matter in treating chronic GVHD",

abstract = "We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease.These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.",

author = "\{van der Wagen\}, Lotte and Julie Janssen and Reinier Raijmakers and Eefke Petersen and \{de Witte\}, Moniek and \{de Jong\}, Niels and Mar Bellido and Ellen Meijer and Brigitte B{\"a}r and \{Jan Boelens\}, Jaap and Alwin Huitema and J{\"u}rgen Kuball",

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T1 - Tyrosine kinase inhibitor levels matter in treating chronic GVHD

AU - van der Wagen, Lotte

AU - Janssen, Julie

AU - Raijmakers, Reinier

AU - Petersen, Eefke

AU - de Witte, Moniek

AU - de Jong, Niels

AU - Bellido, Mar

AU - Meijer, Ellen

AU - Bär, Brigitte

AU - Jan Boelens, Jaap

AU - Huitema, Alwin

AU - Kuball, Jürgen

PY - 2019/7/1

Y1 - 2019/7/1

N2 - We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease.These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.

AB - We observed a possible concentration effect relationship for nilotinib on resolution of chronic Graft versus Host disease.These data suggest therapeutic drug monitoring might be useful for patients receiving tyrosine kinase inhibitors for chronic GVHD.

UR - https://www.scopus.com/pages/publications/85060140726

U2 - 10.1038/s41409-018-0429-5

DO - 10.1038/s41409-018-0429-5

M3 - Letter

C2 - 30651587

AN - SCOPUS:85060140726

SN - 0268-3369

VL - 54

SP - 1141

EP - 1144

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

IS - 7

ER -

Tyrosine kinase inhibitor levels matter in treating chronic GVHD

Abstract

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