@article{b5cb0ebebea948aeab2f0597c15cfc16,
title = "A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening",
abstract = "Leung and colleagues established a biobank of patient-derived gastric cancer organoids that encompasses a diverse array of subtypes and maintained long-term similarity to the original tumors. They used the organoids to perform large-scale drug screening that identified potential target drugs and could guide patient drug selection.",
keywords = "ARHGAP fusions, EBV genome, RHOA mutations, biobank, drug screening, gastric cancer, heterogeneity, organoid culture, transcriptome sequencing, whole-exome sequencing",
author = "Yan, \{Helen H.N.\} and Siu, \{Hoi Cheong\} and Simon Law and Ho, \{Siu Lun\} and Yue, \{Sarah S.K.\} and Tsui, \{Wai Yin\} and Dessy Chan and Chan, \{April S.\} and Stephanie Ma and Lam, \{Ka On\} and Sina Bartfeld and Man, \{Alice H.Y.\} and Lee, \{Bernard C.H.\} and Chan, \{Annie S.Y.\} and Wong, \{Jason W.H.\} and Cheng, \{Priscilla S.W.\} and Chan, \{Anthony K.W.\} and Jiangwen Zhang and Jue Shi and Xiaodan Fan and Kwong, \{Dora L.W.\} and Mak, \{Tak W.\} and Yuen, \{Siu Tsan\} and Hans Clevers and Leung, \{Suet Yi\}",
note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2018",
month = dec,
day = "6",
doi = "10.1016/j.stem.2018.09.016",
language = "English",
volume = "23",
pages = "882--897.e11",
journal = "Cell stem cell",
issn = "1934-5909",
publisher = "Cell Press",
number = "6",
}