A decrease in vitamin D levels is associated with methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia

Keyphrases

• Acute Lymphoblastic Leukemia 100%
• Methotrexate 100%
• Oral mucositis 100%
• 25(OH)D3 100%
• Vitamin D Status 100%
• Vitamin D Deficiency 37%
• Severe Oral mucositis 37%
• Pediatric Acute Lymphoblastic Leukemia 25%
• High-dose Methotrexate (HD-MTX) 25%
• Adverse Events 12%
• Leukemia Patients 12%
• Non-associated 12%
• Methotrexate Treatment 12%
• 25-hydroxyvitamin D (25OHD) 12%
• Prevalence of Vitamin D Deficiency 12%
• Tissue Barrier 12%
• Low Vitamin D 12%
• 24,25-dihydroxyvitamin D 12%
• Mucosal Tissues 12%
• High-dose Methotrexate Therapy 12%

Pharmacology, Toxicology and Pharmaceutical Science

• Methotrexate 100%
• Acute Lymphoblastic Leukemia 100%
• Oral Mucositis 100%
• Vitamin D 100%
• Hypovitaminosis D 66%
• Vitamin D Deficiency 66%
• Adverse Event 16%
• Prevalence 16%
• 24,25 Dihydroxyvitamin D 16%
• 25 Hydroxyvitamin D 16%

Immunology and Microbiology

• Methotrexate 100%
• Drug Megadose 50%
• Prevalence 16%
• Mucosal Tissue 16%