TY - JOUR
T1 - A multicentre epidemiological study on sunbed use and cutaneous melanoma in Europe
AU - Bataille, Véronique
AU - Boniol, Mathieu
AU - De Vries, Esther
AU - Severi, Gianluca
AU - Brandberg, Yvonne
AU - Sasieni, Peter
AU - Cuzick, Jack
AU - Eggermont, Alexander
AU - Ringborg, Ulrik
AU - Grivegnée, André Robert
AU - Coebergh, Jan Willem
AU - Chignol, Marie Christine
AU - Doré, Jean François
AU - Autier, Philippe
N1 - Funding Information:
This study has been supported by the BIOMED II programme of the European Commission, (Grant No. BMH4-98-3682). Neither the European Commission nor any person acting on its behalf is liable for any use made of the content of this article.
PY - 2005/9
Y1 - 2005/9
N2 - A large European case-control study investigated the association between sunbed use and cutaneous melanoma in an adult population aged between 18 and 49 years. Between 1999 and 2001 sun and sunbed exposure was recorded in 597 newly diagnosed melanoma cases and 622 controls in Belgium, France, The Netherlands, Sweden and the UK. Fifty three precent of cases and 57% of controls ever used sunbeds. The overall adjusted odds ratio (OR) associated with ever sunbed use was 0.90 (95% CI: 0.71-1.14). There was a South-to-North gradient with high prevalence of sunbed exposure in Northern Europe and lower prevalence in the South (prevalence of use in France 20%, OR: 1.19 (0.68-2.07) compared to Sweden, prevalence 83%, relative risk 0.62 (0.26-1.46)). Dose and lag-time between first exposure to sunbeds and time of study were not associated with melanoma risk, neither were sunbathing and sunburns (adjusted OR for mean number of weeks spent in sunny climates >14 years: 1.12 (0.88-1.43); adjusted OR for any sunburn >14 years: 1.16 (0.9-1.45)). Host factors such as numbers of naevi and skin type were the strongest risk indicators for melanoma. Public health campaigns have improved knowledge regarding risk of UV-radiation for skin cancers and this may have led to recall and selection biases in both cases and controls in this study. Sunbed exposure has become increasingly prevalent over the last 20 years, especially in Northern Europe but the full impact of this exposure on skin cancers may not become apparent for many years.
AB - A large European case-control study investigated the association between sunbed use and cutaneous melanoma in an adult population aged between 18 and 49 years. Between 1999 and 2001 sun and sunbed exposure was recorded in 597 newly diagnosed melanoma cases and 622 controls in Belgium, France, The Netherlands, Sweden and the UK. Fifty three precent of cases and 57% of controls ever used sunbeds. The overall adjusted odds ratio (OR) associated with ever sunbed use was 0.90 (95% CI: 0.71-1.14). There was a South-to-North gradient with high prevalence of sunbed exposure in Northern Europe and lower prevalence in the South (prevalence of use in France 20%, OR: 1.19 (0.68-2.07) compared to Sweden, prevalence 83%, relative risk 0.62 (0.26-1.46)). Dose and lag-time between first exposure to sunbeds and time of study were not associated with melanoma risk, neither were sunbathing and sunburns (adjusted OR for mean number of weeks spent in sunny climates >14 years: 1.12 (0.88-1.43); adjusted OR for any sunburn >14 years: 1.16 (0.9-1.45)). Host factors such as numbers of naevi and skin type were the strongest risk indicators for melanoma. Public health campaigns have improved knowledge regarding risk of UV-radiation for skin cancers and this may have led to recall and selection biases in both cases and controls in this study. Sunbed exposure has become increasingly prevalent over the last 20 years, especially in Northern Europe but the full impact of this exposure on skin cancers may not become apparent for many years.
KW - Case-control study
KW - Melanoma
KW - Naevus
KW - Sun exposure
KW - Sunbed
UR - http://www.scopus.com/inward/record.url?scp=25144485899&partnerID=8YFLogxK
U2 - 10.1016/j.ejca.2005.04.038
DO - 10.1016/j.ejca.2005.04.038
M3 - Article
C2 - 16125927
AN - SCOPUS:25144485899
SN - 0959-8049
VL - 41
SP - 2141
EP - 2149
JO - European Journal of Cancer
JF - European Journal of Cancer
IS - 14
ER -