A review of the clinical experience in pulsed dose rate brachytherapy

Brian V. Balgobind; Kees Koedooder; Diego Ordoñez Zúñiga; Raquel Dávila Fajardo; Coen R.N. Rasch; Bradley R. Pieters

doi:10.1259/bjr.20150310

A review of the clinical experience in pulsed dose rate brachytherapy

Brian V. Balgobind, Kees Koedooder, Diego Ordoñez Zúñiga, Raquel Dávila Fajardo, Coen R.N. Rasch, Bradley R. Pieters

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel recenseren › peer review

18 Citaten (Scopus)

Samenvatting

Pulsed dose rate (PDR) brachytherapy is a treatment modality that combines physical advantages of high dose rate (HDR) brachytherapy with the radiobiological advantages of low dose rate brachytherapy. The aim of this review was to describe the effective clinical use of PDR brachytherapy worldwide in different tumour locations. We found 66 articles reporting on clinical PDR brachytherapy including the treatment procedure and outcome. Moreover, PDR brachytherapy has been applied in almost all tumour sites for which brachytherapy is indicated and with good local control and low toxicity. The main advantage of PDR is, because of the small pulse sizes used, the ability to spare normal tissue. In certain cases, HDR resembles PDR brachytherapy by the use of multifractionated low-fraction dose.

Originele taal-2	Engels
Tijdschrift	British Journal of Radiology
Volume	88
Nummer van het tijdschrift	1055
DOI's	https://doi.org/10.1259/bjr.20150310
Status	Gepubliceerd - 2015
Extern gepubliceerd	Ja

Toegang tot document

10.1259/bjr.20150310

Citeer dit

@article{543cc50ca92742cfba770d317d3a7282,

title = "A review of the clinical experience in pulsed dose rate brachytherapy",

abstract = "Pulsed dose rate (PDR) brachytherapy is a treatment modality that combines physical advantages of high dose rate (HDR) brachytherapy with the radiobiological advantages of low dose rate brachytherapy. The aim of this review was to describe the effective clinical use of PDR brachytherapy worldwide in different tumour locations. We found 66 articles reporting on clinical PDR brachytherapy including the treatment procedure and outcome. Moreover, PDR brachytherapy has been applied in almost all tumour sites for which brachytherapy is indicated and with good local control and low toxicity. The main advantage of PDR is, because of the small pulse sizes used, the ability to spare normal tissue. In certain cases, HDR resembles PDR brachytherapy by the use of multifractionated low-fraction dose.",

author = "Balgobind, {Brian V.} and Kees Koedooder and Z{\'u}{\~n}iga, {Diego Ordo{\~n}ez} and Fajardo, {Raquel D{\'a}vila} and Rasch, {Coen R.N.} and Pieters, {Bradley R.}",

note = "Publisher Copyright: {\textcopyright} 2015 The Authors. Published by the British Institute of Radiology.",

year = "2015",

doi = "10.1259/bjr.20150310",

language = "English",

volume = "88",

journal = "British Journal of Radiology",

issn = "0007-1285",

publisher = "British Institute of Radiology",

number = "1055",

}

TY - JOUR

T1 - A review of the clinical experience in pulsed dose rate brachytherapy

AU - Balgobind, Brian V.

AU - Koedooder, Kees

AU - Zúñiga, Diego Ordoñez

AU - Fajardo, Raquel Dávila

AU - Rasch, Coen R.N.

AU - Pieters, Bradley R.

PY - 2015

Y1 - 2015

N2 - Pulsed dose rate (PDR) brachytherapy is a treatment modality that combines physical advantages of high dose rate (HDR) brachytherapy with the radiobiological advantages of low dose rate brachytherapy. The aim of this review was to describe the effective clinical use of PDR brachytherapy worldwide in different tumour locations. We found 66 articles reporting on clinical PDR brachytherapy including the treatment procedure and outcome. Moreover, PDR brachytherapy has been applied in almost all tumour sites for which brachytherapy is indicated and with good local control and low toxicity. The main advantage of PDR is, because of the small pulse sizes used, the ability to spare normal tissue. In certain cases, HDR resembles PDR brachytherapy by the use of multifractionated low-fraction dose.

AB - Pulsed dose rate (PDR) brachytherapy is a treatment modality that combines physical advantages of high dose rate (HDR) brachytherapy with the radiobiological advantages of low dose rate brachytherapy. The aim of this review was to describe the effective clinical use of PDR brachytherapy worldwide in different tumour locations. We found 66 articles reporting on clinical PDR brachytherapy including the treatment procedure and outcome. Moreover, PDR brachytherapy has been applied in almost all tumour sites for which brachytherapy is indicated and with good local control and low toxicity. The main advantage of PDR is, because of the small pulse sizes used, the ability to spare normal tissue. In certain cases, HDR resembles PDR brachytherapy by the use of multifractionated low-fraction dose.

UR - http://www.scopus.com/inward/record.url?scp=84945151858&partnerID=8YFLogxK

U2 - 10.1259/bjr.20150310

DO - 10.1259/bjr.20150310

M3 - Review article

C2 - 26290399

AN - SCOPUS:84945151858

SN - 0007-1285

VL - 88

JO - British Journal of Radiology

JF - British Journal of Radiology

IS - 1055

ER -

A review of the clinical experience in pulsed dose rate brachytherapy

Samenvatting

Toegang tot document

Vingerafdruk

Citeer dit