@article{9e8f4466150946408c6646ac396c5fa4,
title = "A twice daily posaconazole dosing algorithm for children with chronic granulomatous disease",
abstract = "Posaconazole (PSZ) may be an attractive alternative for antifungal prophylaxis in children with chronic granulomatous disease. Experience with PSZ in pediatric patients is limited, and no specific dose recommendations exist. A twice daily dosing algorithm based on allometric scaling (body-weight based) for PSZ results in adequate exposure and appears to be safe in children with chronic granulomatous disease.",
keywords = "CGD, children, pharmacokinetics, posaconazole, prophylaxis",
author = "Welzen, {Marieke E.B.} and Br{\"u}ggemann, {Roger J.M.} and {Van Den Berg}, {J. Merlijn} and Voogt, {Heleen W.} and Gilissen, {Jos H.} and Dasja Pajkrt and Nigel Klein and Burger, {David M.} and Adilia Warris",
note = "Funding Information: R.B. has received honoraria for consultancy, speaker's fees, and educational or clinical research grants from Schering-Plough and Pfizer. He has received speaker's fees from Gilead. A.W. has received honoraria for consultancy from Pfizer, Schering-Plough, and Gilead, and educational grants from Pfizer and Gilead. N.K. was supported in part by TEDDY (Task-force in Europe for Drug Development for the Young). All other authors have no conflicts. ",
year = "2011",
month = sep,
doi = "10.1097/INF.0b013e3182195808",
language = "English",
volume = "30",
pages = "794--797",
journal = "Pediatric Infectious Disease Journal",
issn = "0891-3668",
publisher = "Lippincott Williams and Wilkins",
number = "9",
}