@article{cfe0ee52f72b4bacb7f5dc76f8b924db,
title = "Absence of a PDX-1 mutation and normal gastroduodenal immunohistology in a child with pancreatic agenesis",
abstract = "Pancreatic agenesis is a rare condition, of which only a limited number of cases have been described. One recent paper reported a homozygous mutation in the pancreatic duodenal homeobox gene 1 (PDX-1) in a child with pancreatic agenesis. We report a 6-yearold boy with pancreatic agenesis, treated medically, without abnormalities in the PDX-1 gene coding sequence and with normal gastroduodenal endocrine cell distribution. Genes other than PDX-1 also appear to be involved in human pancreatic agenesis.",
keywords = "Agenesis, Immunohistochemistry, Mutation analysis, PDX-1, Pancreas",
author = "Verwest, \{Aart M.\} and Marnix Poelman and Dinjens, \{Winand N.M.\} and Batstra, \{Manou R.\} and Oostra, \{Ben A.\} and Lequin, \{Maarten H.\} and Larsson, \{Lars Inge\} and Aanstoot, \{Henk Jan\} and Bruining, \{G. Jan\} and \{De Krijger\}, \{Ronald R.\}",
note = "Funding Information: Acknowledgements This work was supported by the Child Health and Wellbeing Fund. The authors would like to thank F. van der Ham for excellent technical support.",
year = "2000",
doi = "10.1007/s004280000305",
language = "English",
volume = "437",
pages = "680--684",
journal = "Virchows Archiv",
issn = "0945-6317",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "6",
}