TY - JOUR
T1 - An exclusive case of juvenile myelomonocytic leukemia in association with Kikuchi's disease and hemophagocytic lymphohistiocytosis and a review of the literature
AU - Gerritsen, Annemieke
AU - Lam, King
AU - Marion Schneider, E.
AU - van den Heuvel-Eibrink, Marry M.
PY - 2006/10
Y1 - 2006/10
N2 - We present a case of juvenile myelomonocytic leukemia (JMML) accompanied by immune-mediated hemophagocytic lymphohistiocytosis (HLH) and Kikuchi's disease, both as a paraneoplastic phenomenon. As this combination, to the best of our knowledge, has not been described before, consensus on preferable treatment is lacking. Our patient was treated with prednisolone according to the few described cases of HLH and Kikuchi's disease in non-JMML patients, resulting in disappearance of the clinical symptoms.
AB - We present a case of juvenile myelomonocytic leukemia (JMML) accompanied by immune-mediated hemophagocytic lymphohistiocytosis (HLH) and Kikuchi's disease, both as a paraneoplastic phenomenon. As this combination, to the best of our knowledge, has not been described before, consensus on preferable treatment is lacking. Our patient was treated with prednisolone according to the few described cases of HLH and Kikuchi's disease in non-JMML patients, resulting in disappearance of the clinical symptoms.
KW - Autoimmune phenomena
KW - Hemophagocytic lymphohistiocytosis
KW - Juvenile myelomonocytic leukemia
KW - Kikuchi's disease
UR - http://www.scopus.com/inward/record.url?scp=33747128842&partnerID=8YFLogxK
U2 - 10.1016/j.leukres.2005.12.027
DO - 10.1016/j.leukres.2005.12.027
M3 - Article
C2 - 16487587
AN - SCOPUS:33747128842
SN - 0145-2126
VL - 30
SP - 1299
EP - 1303
JO - Leukemia Research
JF - Leukemia Research
IS - 10
ER -