Samenvatting
Combined efforts of developmental biologists and cancer geneticists have outlined the canonical Wnt/Wingless (Wg) signalling pathway as we currently know it. At the heart of the pathway is the molecule β-catenin/Armadillo. Recent work has shown that the tumour suppressor adenomatous polyposis coli (APC) acts to shuttle β-catenin from the nucleus to the cytoplasm.
Originele taal-2 | Engels |
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Pagina's (van-tot) | E177-E178 |
Tijdschrift | Nature Cell Biology |
Volume | 2 |
Nummer van het tijdschrift | 10 |
DOI's | |
Status | Gepubliceerd - okt. 2000 |
Extern gepubliceerd | Ja |