Armadillo takes the APC shuttle

Hans Clevers

doi:10.1038/35036424

Armadillo takes the APC shuttle

Hans Clevers

Onderzoeksoutput: Bijdrage aan tijdschrift › Kort overzicht › peer review

8 Citaten (Scopus)

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Combined efforts of developmental biologists and cancer geneticists have outlined the canonical Wnt/Wingless (Wg) signalling pathway as we currently know it. At the heart of the pathway is the molecule β-catenin/Armadillo. Recent work has shown that the tumour suppressor adenomatous polyposis coli (APC) acts to shuttle β-catenin from the nucleus to the cytoplasm.

Originele taal-2	Engels
Pagina's (van-tot)	E177-E178
Tijdschrift	Nature Cell Biology
Volume	2
Nummer van het tijdschrift	10
DOI's	https://doi.org/10.1038/35036424
Status	Gepubliceerd - okt. 2000
Extern gepubliceerd	Ja

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10.1038/35036424

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abstract = "Combined efforts of developmental biologists and cancer geneticists have outlined the canonical Wnt/Wingless (Wg) signalling pathway as we currently know it. At the heart of the pathway is the molecule β-catenin/Armadillo. Recent work has shown that the tumour suppressor adenomatous polyposis coli (APC) acts to shuttle β-catenin from the nucleus to the cytoplasm.",

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Armadillo takes the APC shuttle

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