Atypical teratoid/rhabdoid tumor arising in a malignant glioma

Barbara Bozzai, Martin Hasselblatt, Eszter Turányi, Michael C. Frühwald, Reiner Siebert, Susanne Bens, Reinhard Schneppenheim, Marcel Kool, Gábor Stelczer, Tibor Hortobágyi, Peter Hauser

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

8 Citaten (Scopus)


Atypical teratoid/rhabdoid tumor (AT/RT), a highly malignant brain tumor in young children, usually arises de novo and has only rarely been described as a secondary malignancy. Here, we present a case of a child with glioblastoma, who was treated postoperatively by a combination of temozolomide, irradiation, and bevacizumab. AT/RT was diagnosed as a secondary tumor, 2.5 years following primary diagnosis. The child died 13 months after the diagnosis of AT/RT. This case demonstrates that malignant gliomas may give rise to AT/RT. It also emphasizes the diagnostic value of a repeated tumor biopsy in the recurrence setting.

Originele taal-2Engels
Pagina's (van-tot)96-99
Aantal pagina's4
TijdschriftPediatric Blood and Cancer
Nummer van het tijdschrift1
StatusGepubliceerd - 1 jan. 2017
Extern gepubliceerdJa


Duik in de onderzoeksthema's van 'Atypical teratoid/rhabdoid tumor arising in a malignant glioma'. Samen vormen ze een unieke vingerafdruk.

Citeer dit