Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment

R Jung; U Jacobs; M Krumbholz; T Langer; T Keller; P De Lorenzo; M G Valsecchi; V H J van der Velden; A Moericke; M Stanulla; A Teigler-Schlegel; E R Panzer-Gruemayer; J J M van Dongen; M Schrappe; M L den Boer; R Pieters; W Rascher; M Metzler

doi:10.1038/leu.2010.14

Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment

R Jung, U Jacobs, M Krumbholz, T Langer, T Keller, P De Lorenzo, M G Valsecchi, V H J van der Velden, A Moericke, M Stanulla, A Teigler-Schlegel, E R Panzer-Gruemayer, J J M van Dongen, M Schrappe, M L den Boer, R Pieters, W Rascher, M Metzler

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

12 Citaten (Scopus)

Originele taal-2	Engels
Pagina's (van-tot)	903-7
Aantal pagina's	5
Tijdschrift	Leukemia
Volume	24
Nummer van het tijdschrift	4
DOI's	https://doi.org/10.1038/leu.2010.14
Status	Gepubliceerd - apr. 2010
Extern gepubliceerd	Ja

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10.1038/leu.2010.14

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Jung, R., Jacobs, U., Krumbholz, M., Langer, T., Keller, T., De Lorenzo, P., Valsecchi, M. G., van der Velden, V. H. J., Moericke, A., Stanulla, M., Teigler-Schlegel, A., Panzer-Gruemayer, E. R., van Dongen, J. J. M., Schrappe, M., den Boer, M. L., Pieters, R., Rascher, W., & Metzler, M. (2010). Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment. Leukemia, 24(4), 903-7. https://doi.org/10.1038/leu.2010.14

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title = "Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment",

keywords = "Adolescent, Child, Child, Preschool, Chromosome Breakpoints, Cohort Studies, DNA-Binding Proteins/genetics, Enzyme Inhibitors/pharmacology, Female, Histone-Lysine N-Methyltransferase, Humans, Infant, Male, Myeloid-Lymphoid Leukemia Protein/genetics, Nuclear Proteins/genetics, Oncogene Proteins, Fusion/genetics, Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics, Pregnancy, Prenatal Exposure Delayed Effects, Recombination, Genetic, Survival Rate, Topoisomerase II Inhibitors, Transcriptional Elongation Factors",

author = "R Jung and U Jacobs and M Krumbholz and T Langer and T Keller and {De Lorenzo}, P and Valsecchi, {M G} and {van der Velden}, {V H J} and A Moericke and M Stanulla and A Teigler-Schlegel and Panzer-Gruemayer, {E R} and {van Dongen}, {J J M} and M Schrappe and {den Boer}, {M L} and R Pieters and W Rascher and M Metzler",

note = "Funding Information: We thank all members of the participating INTERFANT-99 study groups for providing patients samples and clinical data. This study was supported by a Wilhelm–Sander Foundation grant to MM and TL. RJ was supported by a grant from the Carreras Foundation. ERP-G was supported by GENAU-CHILD Project GZ200.136/1FVI/1/2005 and the St Anna Kinderkrebsforschung. Funding Information: We wish to thank Mrs Dominique Bouchot, Martine Courtois, Isabelle Helot and Aur{\'e}lie Herry (CHU Dijon), for excellent technical help, and Philip Bastable for revisions. This work was supported by a grant from the Ligue contre le Cancer, Comit{\'e} de C{\^o}te d{\textquoteright}Or.",

year = "2010",

month = apr,

doi = "10.1038/leu.2010.14",

language = "English",

volume = "24",

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journal = "Leukemia",

issn = "0887-6924",

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Jung, R, Jacobs, U, Krumbholz, M, Langer, T, Keller, T, De Lorenzo, P, Valsecchi, MG, van der Velden, VHJ, Moericke, A, Stanulla, M, Teigler-Schlegel, A, Panzer-Gruemayer, ER, van Dongen, JJM, Schrappe, M, den Boer, ML , Pieters, R, Rascher, W & Metzler, M 2010, 'Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment', Leukemia, vol. 24, nr. 4, blz. 903-7. https://doi.org/10.1038/leu.2010.14

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AU - Jung, R

AU - Jacobs, U

AU - Krumbholz, M

AU - Langer, T

AU - Keller, T

AU - De Lorenzo, P

AU - Valsecchi, M G

AU - van der Velden, V H J

AU - Moericke, A

AU - Stanulla, M

AU - Teigler-Schlegel, A

AU - Panzer-Gruemayer, E R

AU - van Dongen, J J M

AU - Schrappe, M

AU - den Boer, M L

AU - Pieters, R

AU - Rascher, W

AU - Metzler, M

N1 - Funding Information: We thank all members of the participating INTERFANT-99 study groups for providing patients samples and clinical data. This study was supported by a Wilhelm–Sander Foundation grant to MM and TL. RJ was supported by a grant from the Carreras Foundation. ERP-G was supported by GENAU-CHILD Project GZ200.136/1FVI/1/2005 and the St Anna Kinderkrebsforschung. Funding Information: We wish to thank Mrs Dominique Bouchot, Martine Courtois, Isabelle Helot and Aurélie Herry (CHU Dijon), for excellent technical help, and Philip Bastable for revisions. This work was supported by a grant from the Ligue contre le Cancer, Comité de Côte d’Or.

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KW - Child, Preschool

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KW - Infant

KW - Male

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KW - Nuclear Proteins/genetics

KW - Oncogene Proteins, Fusion/genetics

KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics

KW - Pregnancy

KW - Prenatal Exposure Delayed Effects

KW - Recombination, Genetic

KW - Survival Rate

KW - Topoisomerase II Inhibitors

KW - Transcriptional Elongation Factors

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U2 - 10.1038/leu.2010.14

DO - 10.1038/leu.2010.14

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C2 - 20164851

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JF - Leukemia

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