Biologicals as theranostic vehicles in paediatric oncology

Veerle J.A. Niessen, Sylvia T.M. Wenker, Marnix G.E.H. Lam, Max M. van Noesel, Alex J. Poot

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review


Biologicals, such as antibodies or antibody-fragments e.g. nanobodies, have changed the landscape of cancer therapy and can be used in combination with traditional cancer treatments. They have been demonstrated to be excellent vehicles for molecular imaging. Several biologicals for nuclear imaging of adult cancer may be used in combination with (nuclear) therapy. Though it's great potential, molecular imaging using biologicals is rarely applied in paediatric oncology. This paper describes the current status of biologicals as radiopharmaceuticals for childhood cancer. Furthermore, the importance and potential for developing additional biological theranostics as opportunity to image and treat childhood cancer is discussed.

Originele taal-2Engels
Pagina's (van-tot)58-64
Aantal pagina's7
TijdschriftNuclear Medicine and Biology
StatusGepubliceerd - 1 nov. 2022


  • Biologicals
  • Nuclear imaging
  • Paediatric oncology
  • Radionuclide therapy
  • Theranostics


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