Biology and Treatment of Acute Lymphoblastic Leukemia

Rob Pieters, William L. Carroll

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

83 Citaten (Scopus)


Acute lymphoblastic leukemia (ALL), the most common type of cancer in children, is a heterogeneous disease in which many genetic lesions result in the development of multiple biologic subtypes. Today, with intensive multiagent chemotherapy, most children who have ALL are cured. The many national or institutional ALL therapy protocols in use tend to stratify patients in a multitude of different ways to tailor treatment to the rate of relapse. This article discusses the factors used in risk stratification and the treatment of pediatric ALL.

Originele taal-2Engels
Pagina's (van-tot)1-18
Aantal pagina's18
TijdschriftHematology/Oncology Clinics of North America
Nummer van het tijdschrift1
StatusGepubliceerd - feb. 2010
Extern gepubliceerdJa


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