TY - JOUR
T1 - Bone Marrow Transplantation for Pompé's Disease
AU - Hoogerbrugge, P. M.
AU - Wagemaker, G.
AU - Van Bekkum, D. W.
AU - Reuser, A. J.J.
AU - Van Den Ploeg, A. T.
PY - 1986/7/3
Y1 - 1986/7/3
N2 - To the Editor: Watson et al. report performing an allogeneic bone marrow transplantation in a 16-month-old child with Pompé's disease (Feb. 6 issue).1 Because the patient died on day 33 after transplantation, the long-term effects of the procedure could not be evaluated. Despite this, the authors encourage further attempts at treatment of Pompé's disease with bone marrow transplants. Their only argument in favor of this recommendation seems to be that acid maltase, the enzyme that is deficient in Pompé's disease, may be supplied by enzyme-competent bone marrow cells. The authors do not take into account the complicated molecular and cellular., No extract is available for articles shorter than 400 words.
AB - To the Editor: Watson et al. report performing an allogeneic bone marrow transplantation in a 16-month-old child with Pompé's disease (Feb. 6 issue).1 Because the patient died on day 33 after transplantation, the long-term effects of the procedure could not be evaluated. Despite this, the authors encourage further attempts at treatment of Pompé's disease with bone marrow transplants. Their only argument in favor of this recommendation seems to be that acid maltase, the enzyme that is deficient in Pompé's disease, may be supplied by enzyme-competent bone marrow cells. The authors do not take into account the complicated molecular and cellular., No extract is available for articles shorter than 400 words.
UR - http://www.scopus.com/inward/record.url?scp=0022602909&partnerID=8YFLogxK
U2 - 10.1056/NEJM198607033150117
DO - 10.1056/NEJM198607033150117
M3 - Letter
C2 - 3086726
AN - SCOPUS:0022602909
SN - 0028-4793
VL - 315
SP - 65
EP - 66
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 1
ER -