C12orf57: a novel principal regulator of synaptic AMPA currents and excitatory neuronal homeostasis

Keyphrases

• Synaptic 100%
• Neuronal Homeostasis 100%
• C12orf57 100%
• Homeostasis 75%
• Knock-in Mouse Model 50%
• Epilepsy 50%
• Novel Mechanism 50%
• AMPA Receptor (AMPAR) 50%
• Downscaling 50%
• Temtamy Syndrome 50%
• Amino Acids 25%
• Upstream Open Reading Frame (uORF) 25%
• Molecular Mechanism 25%
• Biallelic 25%
• Expression Level 25%
• Receptor Expression 25%
• Corpus Callosum Agenesis 25%
• Autism 25%
• In Vitro Assay 25%
• Phenotypic Characteristics 25%
• Genetic Mechanism 25%
• Gain-of-function mutation 25%
• Neuronal Survival 25%
• Hippocampal Neurons 25%
• Increased Activity 25%
• Multiple Lines 25%
• Orthologs 25%
• Glutamatergic Neurons 25%
• Epileptiform Activity 25%
• Seizure Susceptibility 25%
• Calcium-dependent Protein Kinase 25%
• Survival Circuits 25%
• Circuit Function 25%
• Recurrent Losses 25%
• Evolutionarily Conserved 25%
• Severe Intellectual Disability 25%
• Circuit Plasticity 25%
• High Amplitudes 25%
• MEPSC 25%

Neuroscience

• AMPA Receptor 100%
• AMPA 100%
• Intellectual Disability 100%
• Epilepsy 100%
• In Vitro 50%
• Corpus Callosum 50%
• Kinase 50%
• Neurodevelopmental Disorder 50%
• Receptor Expression 50%
• Amino Acid 50%
• Loss of Function Mutation 50%
• Open Reading Frame 50%
• Excitatory Postsynaptic Potential 50%
• CREB 50%
• Calmodulin 50%
• Autism 50%
• Genetics 50%

Biochemistry, Genetics and Molecular Biology

• Homeostasis 100%
• Amino Methyl Phosphonic Acid 100%
• Knockout Mouse 40%
• Intellectual Disability 40%
• AMPA Receptor 40%
• Genetics 20%
• Amino Acids 20%
• Open Reading Frame 20%
• Mouse Model 20%
• Kinase 20%
• Phosphotransferase 20%
• CREB 20%
• Loss of Function Mutation 20%
• Orthology 20%
• Calmodulin 20%
• Excitatory Postsynaptic Potential 20%
• Glutamatergic 20%
• Expression Level 20%
• Molecular Mechanism 20%