Cavitation-Enhanced Back Projection for Acoustic Rib Detection and Attenuation Mapping

Pascal Ramaekers, Martijn de Greef, Chrit T.W. Moonen, Mario G. Ries

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

4 Citaten (Scopus)


High-intensity focused ultrasound allows for minimally invasive, highly localized cancer therapies that can complement surgical procedures or chemotherapy. For high-intensity focused ultrasound interventions in the upper abdomen, the thoracic cage obstructs and aberrates the ultrasonic beam, causing undesired heating of healthy tissue. When a phased array therapeutic transducer is used, such complications can be minimized by applying an apodization law based on analysis of beam path obstructions. In this work, a rib detection method based on cavitation-enhanced ultrasonic reflections is introduced and validated on a porcine tissue sample containing ribs. Apodization laws obtained for different transducer positions were approximately 90% similar to those obtained using image analysis. Additionally, the proposed method provides information on attenuation between transducer elements and the focus. This principle was confirmed experimentally on a polymer phantom. The proposed methods could, in principle, be implemented in real time for determination of the optimal shot position in intercostal high-intensity focused ultrasound therapy.

Originele taal-2Engels
Pagina's (van-tot)1726-1736
Aantal pagina's11
TijdschriftUltrasound in Medicine and Biology
Nummer van het tijdschrift6
StatusGepubliceerd - 1 jun. 2015
Extern gepubliceerdJa


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