Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

Gert Jan Timmers; Dannis G van Vuurden; Eleonora L Swart; Alberdina M Simoons-Smit; Peter C Huijgens

Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

Gert Jan Timmers
, Dannis G van Vuurden
, Eleonora L Swart
, Alberdina M Simoons-Smit
, Peter C Huijgens

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

8 Citaten (Scopus)

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Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

Originele taal-2	Engels
Pagina's (van-tot)	1005-6
Aantal pagina's	2
Tijdschrift	Haematologica
Volume	90
Nummer van het tijdschrift	7
Status	Gepubliceerd - jul. 2005
Extern gepubliceerd	Ja

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title = "Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies",

abstract = "Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.",

keywords = "Aged, Anti-Bacterial Agents/therapeutic use, Cephalosporins/therapeutic use, Female, Fever/drug therapy, Hematologic Neoplasms/drug therapy, Humans, Male, Middle Aged, Neutropenia/drug therapy",

author = "Timmers, \{Gert Jan\} and \{van Vuurden\}, \{Dannis G\} and Swart, \{Eleonora L\} and Simoons-Smit, \{Alberdina M\} and Huijgens, \{Peter C\}",

year = "2005",

month = jul,

language = "English",

volume = "90",

pages = "1005--6",

journal = "Haematologica",

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T1 - Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

AU - Timmers, Gert Jan

AU - van Vuurden, Dannis G

AU - Swart, Eleonora L

AU - Simoons-Smit, Alberdina M

AU - Huijgens, Peter C

PY - 2005/7

Y1 - 2005/7

N2 - Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

AB - Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

KW - Aged

KW - Anti-Bacterial Agents/therapeutic use

KW - Cephalosporins/therapeutic use

KW - Female

KW - Fever/drug therapy

KW - Hematologic Neoplasms/drug therapy

KW - Humans

KW - Male

KW - Middle Aged

KW - Neutropenia/drug therapy

M3 - Article

C2 - 15996951

SN - 0390-6078

VL - 90

SP - 1005

EP - 1006

JO - Haematologica

JF - Haematologica

IS - 7

ER -

Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

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