TY - JOUR
T1 - Children of non-Western origin with end-stage renal disease in the Netherlands, Belgium and a part of Germany have impaired health-related quality of life compared with Western children
AU - Schoenmaker, Nikki J.
AU - Haverman, Lotte
AU - Tromp, Wilma F.
AU - Van Der Lee, Johanna H.
AU - Offringa, Martin
AU - Adams, Brigitte
AU - Bouts, Antonia H.M.
AU - Collard, Laure
AU - Cransberg, Karlien
AU - Van Dyck, Maria
AU - Godefroid, Nathalie
AU - Van Hoeck, Koenraad
AU - Koster-Kamphuis, Linda
AU - Lilien, Marc R.
AU - Raes, Ann
AU - Taylan, Christina
AU - Grootenhuis, Martha A.
AU - Groothoff, Jaap W.
N1 - Funding Information:
This study was performed as part of the RICH-Q project, which is mainly funded by the Dutch Kidney Foundation. Additional funding was provided by Astellas, Ferring Pharmaceuticals, Genzyme, Roche and Shire. The funders had no role in the design and conduct of the project, data gathering or interpretation, or in the preparation of the manuscript.
PY - 2014/2
Y1 - 2014/2
N2 - Background. Many children with end-stage renal disease (ESRD) living in Western Europe are of non-Western European origin. They have unfavourable somatic outcomes compared with ESRD children of Western origin. In this study, we compared the Health-related Quality of Life (HRQoL) of both groups. Methods. All children (5-18 years) with ESRD included in the RICH-Q project (Renal Insufficiency therapy in Children-Quality assessment and improvement) or their parents were asked to complete the generic version of the Paediatric Quality-of-Life Inventory 4.0 (PedsQL). RICH-Q comprises the Netherlands, Belgium and a part of Germany. Children were considered to be of non-Western origin if they or at least one parent was born outside Western-European countries. Impaired HRQoL for children with ESRD of Western or non-Western origin was defined as a PedsQL score less than fifth percentile for healthy Dutch children of Western or non-Western origin, respectively. Results. Of the 259 eligible children, 230 agreed to participate. One hundred and seventy-four children responded (response rate 67%) and 55 (32%) were of non-Western origin. Overall, 31 (56%) of the ESRD children of non-Western origin, and 58 (49%) of Western origin had an impaired total HRQoL score. Total HRQoL scores of children with ESRD of Western origin and non-Western origin were comparable, but scores on emotional functioning and school functioning were lower in non-Western origin (P = 0.004 and 0.01, respectively). The adjusted odds ratios (95% confidence interval) for ESRD children of non-Western origin to have impaired emotional functioning and school functioning, compared with Western origin, were 3.3(1.5-7.1) and 2.2(1.1-4.2), respectively.ConclusionChildren with ESRD of non-Western origin in three Western countries were found to be at risk for impaired HRQoL on emotional and school functioning. These children warrant special attention.
AB - Background. Many children with end-stage renal disease (ESRD) living in Western Europe are of non-Western European origin. They have unfavourable somatic outcomes compared with ESRD children of Western origin. In this study, we compared the Health-related Quality of Life (HRQoL) of both groups. Methods. All children (5-18 years) with ESRD included in the RICH-Q project (Renal Insufficiency therapy in Children-Quality assessment and improvement) or their parents were asked to complete the generic version of the Paediatric Quality-of-Life Inventory 4.0 (PedsQL). RICH-Q comprises the Netherlands, Belgium and a part of Germany. Children were considered to be of non-Western origin if they or at least one parent was born outside Western-European countries. Impaired HRQoL for children with ESRD of Western or non-Western origin was defined as a PedsQL score less than fifth percentile for healthy Dutch children of Western or non-Western origin, respectively. Results. Of the 259 eligible children, 230 agreed to participate. One hundred and seventy-four children responded (response rate 67%) and 55 (32%) were of non-Western origin. Overall, 31 (56%) of the ESRD children of non-Western origin, and 58 (49%) of Western origin had an impaired total HRQoL score. Total HRQoL scores of children with ESRD of Western origin and non-Western origin were comparable, but scores on emotional functioning and school functioning were lower in non-Western origin (P = 0.004 and 0.01, respectively). The adjusted odds ratios (95% confidence interval) for ESRD children of non-Western origin to have impaired emotional functioning and school functioning, compared with Western origin, were 3.3(1.5-7.1) and 2.2(1.1-4.2), respectively.ConclusionChildren with ESRD of non-Western origin in three Western countries were found to be at risk for impaired HRQoL on emotional and school functioning. These children warrant special attention.
KW - PedsQL
KW - end-stage renal disease
KW - non-Western origin
KW - paediatric nephrology
UR - https://www.scopus.com/pages/publications/84896727125
U2 - 10.1093/ndt/gft436
DO - 10.1093/ndt/gft436
M3 - Article
C2 - 24235076
AN - SCOPUS:84896727125
SN - 0931-0509
VL - 29
SP - 448
EP - 457
JO - Nephrology Dialysis Transplantation
JF - Nephrology Dialysis Transplantation
IS - 2
ER -