Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline

Keyphrases

• Chromothripsis 100%
• Germ Cells 100%
• Structural Variation 100%
• Congenital Disorders 100%
• Structural Rearrangement 100%
• Chromosomal Fragment 100%
• Cancer Cells 50%
• Mutational Mechanism 50%
• Structural Variants 50%
• Chromosome 4 50%
• Human Genome 50%
• Chromosome 10 50%
• Chromosome 1 50%
• Non-homologous End Joining 50%
• DNA Double-strand Breaks 50%
• Congenital Abnormalities 50%
• Mate-pair Sequencing 50%
• Interchromosomal 50%
• Structural Change 50%
• Breakpoint Regions 50%
• Junction Point 50%
• Dynamic Architecture 50%
• Somatic Rearrangement 50%
• Intrachromosomal Rearrangements 50%

Biochemistry, Genetics and Molecular Biology

• Chromothripsis 100%
• Germline 100%
• Germ Cell 100%
• Cancer Cell 50%
• Chromosome 4 50%
• Human Genome 50%
• Chromosome 1 50%
• Chromosome 10 50%
• Indel 50%
• Non-Homologous End Joining 50%
• Chromosomal Rearrangement 50%
• Double Stranded DNA Break 50%