TY - JOUR
T1 - Clinical Characteristics of Invasive Fungal Infections in Pediatric Oncology Patients with Solid Tumors
AU - Ruijters, Veerle J.
AU - Oosterom, Natanja
AU - Van Der Perk, Madeleine E.M.
AU - Wolfs, Tom F.W.
AU - Meijer, Annelot J.M.
AU - Van Den Heuvel-Eibrink, Marry M.
AU - Van Grotel, Martine
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/4
Y1 - 2021/4
N2 - Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in children with cancer. Studies on the clinical characteristics of IFI in children with solid tumors are limited. This Dutch retrospective cohort study reviewed the medical records of 61 children with solid tumors to analyze the clinical characteristics during their full treatment period. Seven IFI episodes were reported in 6/61 patients (10%), all diagnosed with intermediate-risk or high-risk Wilms tumor or neuroblastoma. Larger studies are necessary to reveal the determinants of IFI in this group of patients and the value of fungal prophylaxis.
AB - Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in children with cancer. Studies on the clinical characteristics of IFI in children with solid tumors are limited. This Dutch retrospective cohort study reviewed the medical records of 61 children with solid tumors to analyze the clinical characteristics during their full treatment period. Seven IFI episodes were reported in 6/61 patients (10%), all diagnosed with intermediate-risk or high-risk Wilms tumor or neuroblastoma. Larger studies are necessary to reveal the determinants of IFI in this group of patients and the value of fungal prophylaxis.
KW - clinical characteristics
KW - frequency
KW - invasive fungal infections
KW - pediatric oncology patients
UR - http://www.scopus.com/inward/record.url?scp=85103473790&partnerID=8YFLogxK
U2 - 10.1097/MPH.0000000000001761
DO - 10.1097/MPH.0000000000001761
M3 - Article
C2 - 32097283
AN - SCOPUS:85103473790
SN - 1077-4114
VL - 43
SP - e408-e413
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 3
ER -