Clinical evaluation of vancomycin dosage in pediatric oncology patients

Stefan J.W.J. Sanders; Yuma A. Bijleveld; Fleur Sinkeler; Elles M. Kemper; Dasja Pajkrt; Marianne Van De Wetering; Natasha K.A. Van Eijkelenburg; Ron A.A. Mathôt

doi:10.1097/INF.0000000000000268

Clinical evaluation of vancomycin dosage in pediatric oncology patients

Stefan J.W.J. Sanders, Yuma A. Bijleveld, Fleur Sinkeler, Elles M. Kemper, Dasja Pajkrt, Marianne Van De Wetering, Natasha K.A. Van Eijkelenburg, Ron A.A. Mathôt

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

5 Citaten (Scopus)

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Vancomycin trough serum concentrations were below therapeutic range (8-15 mg/L) in 58% of 124 pediatric oncology patients receiving 60 mg/kg/d divided qid. Patients <6 and between 6 and 12 years had significantly lower trough concentrations than patients >12 years. A vancomycin dosage of 60 mg/kg/d is inadequate for pediatric oncology patients >12 years.

Originele taal-2	Engels
Pagina's (van-tot)	731-733
Aantal pagina's	3
Tijdschrift	Pediatric Infectious Disease Journal
Volume	33
Nummer van het tijdschrift	7
DOI's	https://doi.org/10.1097/INF.0000000000000268
Status	Gepubliceerd - jul. 2014
Extern gepubliceerd	Ja

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10.1097/INF.0000000000000268

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title = "Clinical evaluation of vancomycin dosage in pediatric oncology patients",

abstract = "Vancomycin trough serum concentrations were below therapeutic range (8-15 mg/L) in 58\% of 124 pediatric oncology patients receiving 60 mg/kg/d divided qid. Patients <6 and between 6 and 12 years had significantly lower trough concentrations than patients >12 years. A vancomycin dosage of 60 mg/kg/d is inadequate for pediatric oncology patients >12 years.",

keywords = "pediatric oncology, serum concentrations, vancomycin",

author = "Sanders, \{Stefan J.W.J.\} and Bijleveld, \{Yuma A.\} and Fleur Sinkeler and Kemper, \{Elles M.\} and Dasja Pajkrt and \{Van De Wetering\}, Marianne and \{Van Eijkelenburg\}, \{Natasha K.A.\} and Math{\^o}t, \{Ron A.A.\}",

year = "2014",

month = jul,

doi = "10.1097/INF.0000000000000268",

language = "English",

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AU - Sanders, Stefan J.W.J.

AU - Bijleveld, Yuma A.

AU - Sinkeler, Fleur

AU - Kemper, Elles M.

AU - Pajkrt, Dasja

AU - Van De Wetering, Marianne

AU - Van Eijkelenburg, Natasha K.A.

AU - Mathôt, Ron A.A.

PY - 2014/7

Y1 - 2014/7

N2 - Vancomycin trough serum concentrations were below therapeutic range (8-15 mg/L) in 58% of 124 pediatric oncology patients receiving 60 mg/kg/d divided qid. Patients <6 and between 6 and 12 years had significantly lower trough concentrations than patients >12 years. A vancomycin dosage of 60 mg/kg/d is inadequate for pediatric oncology patients >12 years.

AB - Vancomycin trough serum concentrations were below therapeutic range (8-15 mg/L) in 58% of 124 pediatric oncology patients receiving 60 mg/kg/d divided qid. Patients <6 and between 6 and 12 years had significantly lower trough concentrations than patients >12 years. A vancomycin dosage of 60 mg/kg/d is inadequate for pediatric oncology patients >12 years.

KW - pediatric oncology

KW - serum concentrations

KW - vancomycin

UR - https://www.scopus.com/pages/publications/84902549373

U2 - 10.1097/INF.0000000000000268

DO - 10.1097/INF.0000000000000268

M3 - Article

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AN - SCOPUS:84902549373

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SP - 731

EP - 733

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 7

ER -

Clinical evaluation of vancomycin dosage in pediatric oncology patients

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