@article{e46cecc46ce94233a5ae390fd48189b5,
title = "Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group",
abstract = "Patients with childhood, adolescent, and young adult cancer who will be treated with gonadotoxic therapies are at increased risk for infertility. Many patients and their families desire biological children but effective communication about treatment-related infertility risk and procedures for fertility preservation does not always happen. The PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group reviewed the literature and developed a clinical practice guideline that provides recommendations for ongoing communication methods for fertility preservation for patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger and their families. Moreover, the guideline panel formulated considerations of the ethical implications that are associated with these procedures. Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the evidence and recommendations. In this clinical practice guideline, existing evidence and international expertise are combined to develop transparent recommendations that are easy to use to facilitate ongoing communication between health-care providers and patients with childhood, adolescent, and young adult cancer who might be at high risk for fertility impairment and their families.",
keywords = "Adolescent, Adult, Cancer Survivors, Child, Disease Progression, Female, Fertility Preservation/ethics, Guidelines as Topic, Humans, Male, Neoplasms/complications, Young Adult",
author = "{PanCareLIFE Consortium} and Mulder, {Ren{\'e}e L} and Anna Font-Gonzalez and {van Dulmen-den Broeder}, Eline and Quinn, {Gwendolyn P} and Ginsberg, {Jill P} and Loeffen, {Erik A H} and Hudson, {Melissa M} and Burns, {Karen C} and {van Santen}, {Hanneke M} and Claire Berger and Tamara Diesch and Uta Dirksen and Aleksander Giwercman and Clarisa Gracia and Hunter, {Sarah E} and Kelvin, {Joanne F} and Klosky, {James L} and Laven, {Joop S E} and Lockart, {Barbara A} and Neggers, {Sebastian J C M M} and Michelle Peate and Bob Phillips and Reed, {Damon R} and Tinner, {Eva Maria E} and Julianne Byrne and Margreet Veening and {van de Berg}, Marleen and Verhaak, {Chris M} and Antoinette Anazodo and Kenny Rodriguez-Wallberg and {van den Heuvel-Eibrink}, {Marry M} and Asogwa, {Ogechukwu A} and Alexandra Brownsdon and Wallace, {W Hamish} and Green, {Daniel M} and Roderick Skinner and Riccardo Haupt and Kenney, {Lisa B} and Jennifer Levine and {van de Wetering}, {Marianne D} and Tissing, {Wim J E} and Paul, {Norbert W} and Kremer, {Leontien C M} and Julia Inthorn",
note = "Copyright {\textcopyright} 2021 Elsevier Ltd. All rights reserved.",
year = "2021",
month = feb,
doi = "10.1016/S1470-2045(20)30595-7",
language = "English",
volume = "22",
pages = "e68--e80",
journal = "The Lancet Oncology",
issn = "1474-5488",
number = "2",
}