Congenital mesoblastic nephroma 50 years after its recognition: A narrative review

S. L. Gooskens; M. E. Houwing; G. M. Vujanic; J. S. Dome; T. Diertens; A. Coulomb-l'Herminé; J. Godzinski; K. Pritchard-Jones; N. Graf; M. M. van den Heuvel-Eibrink

doi:10.1002/pbc.26437

Congenital mesoblastic nephroma 50 years after its recognition: A narrative review

S. L. Gooskens, M. E. Houwing, G. M. Vujanic, J. S. Dome, T. Diertens, A. Coulomb-l'Herminé, J. Godzinski, K. Pritchard-Jones, N. Graf, M. M. van den Heuvel-Eibrink

Group van den Heuvel

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel recenseren › peer review

101 Citaten (Scopus)

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Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

Originele taal-2	Engels
Artikelnummer	e26437
Tijdschrift	Pediatric Blood and Cancer
Volume	64
Nummer van het tijdschrift	7
DOI's	https://doi.org/10.1002/pbc.26437
Status	Gepubliceerd - jul. 2017

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title = "Congenital mesoblastic nephroma 50 years after its recognition: A narrative review",

abstract = "Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.",

keywords = "clinical characteristics, congenital mesoblastic nephroma, genetics, histology, infancy, outcome, renal tumor, review, treatment",

author = "Gooskens, \{S. L.\} and Houwing, \{M. E.\} and Vujanic, \{G. M.\} and Dome, \{J. S.\} and T. Diertens and A. Coulomb-l'Hermin{\'e} and J. Godzinski and K. Pritchard-Jones and N. Graf and \{van den Heuvel-Eibrink\}, \{M. M.\}",

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doi = "10.1002/pbc.26437",

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AU - Gooskens, S. L.

AU - Houwing, M. E.

AU - Vujanic, G. M.

AU - Dome, J. S.

AU - Diertens, T.

AU - Coulomb-l'Herminé, A.

AU - Godzinski, J.

AU - Pritchard-Jones, K.

AU - Graf, N.

AU - van den Heuvel-Eibrink, M. M.

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N2 - Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

AB - Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

KW - clinical characteristics

KW - congenital mesoblastic nephroma

KW - genetics

KW - histology

KW - infancy

KW - outcome

KW - renal tumor

KW - review

KW - treatment

UR - https://www.scopus.com/pages/publications/85019558072

U2 - 10.1002/pbc.26437

DO - 10.1002/pbc.26437

M3 - Review article

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AN - SCOPUS:85019558072

SN - 1545-5009

VL - 64

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 7

M1 - e26437

ER -

Congenital mesoblastic nephroma 50 years after its recognition: A narrative review

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