TY - JOUR
T1 - Cytogenetic classification of renal cell cancer
AU - Van den Berg, Eva
AU - Dijkhuizen, T.
AU - Oosterhuis, J. Wolter
AU - Van Kessel, Ad Geurts
AU - De Jong, Bauke
AU - Stö̈rkel, Stephan
PY - 1997/5
Y1 - 1997/5
N2 - Cytogenetic and molecular genetic investigations in cancer are important tools to address problems of oncegenesis and tumor progression, of classification, and of diagnosis of tumors. A combination of advanced molecular genetic, cytogenetic, and (immuno) histopathologic analysis will contribute significantly to the elucidation of the oncogenic steps that lead to immortalization and subsequent malignant behavior. In this review written on the occasion of Dr. Avery Sandberg's 75th anniversary, we will present a model for the pathogenesis of renal cell tumors based on a new cytomorphologic classification and our (cyto)genetic analysis of about 175 renal cell tumors, together with the accumulation data in the litetature.
AB - Cytogenetic and molecular genetic investigations in cancer are important tools to address problems of oncegenesis and tumor progression, of classification, and of diagnosis of tumors. A combination of advanced molecular genetic, cytogenetic, and (immuno) histopathologic analysis will contribute significantly to the elucidation of the oncogenic steps that lead to immortalization and subsequent malignant behavior. In this review written on the occasion of Dr. Avery Sandberg's 75th anniversary, we will present a model for the pathogenesis of renal cell tumors based on a new cytomorphologic classification and our (cyto)genetic analysis of about 175 renal cell tumors, together with the accumulation data in the litetature.
UR - http://www.scopus.com/inward/record.url?scp=0030929318&partnerID=8YFLogxK
U2 - 10.1016/S0165-4608(96)00289-0
DO - 10.1016/S0165-4608(96)00289-0
M3 - Article
C2 - 9140459
AN - SCOPUS:0030929318
SN - 0165-4608
VL - 95
SP - 103
EP - 107
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -