Cytogenetic classification of renal cell cancer

Eva Van den Berg, T. Dijkhuizen, J. Wolter Oosterhuis, Ad Geurts Van Kessel, Bauke De Jong, Stephan Stö̈rkel

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

59 Citaten (Scopus)

Samenvatting

Cytogenetic and molecular genetic investigations in cancer are important tools to address problems of oncegenesis and tumor progression, of classification, and of diagnosis of tumors. A combination of advanced molecular genetic, cytogenetic, and (immuno) histopathologic analysis will contribute significantly to the elucidation of the oncogenic steps that lead to immortalization and subsequent malignant behavior. In this review written on the occasion of Dr. Avery Sandberg's 75th anniversary, we will present a model for the pathogenesis of renal cell tumors based on a new cytomorphologic classification and our (cyto)genetic analysis of about 175 renal cell tumors, together with the accumulation data in the litetature.

Originele taal-2Engels
Pagina's (van-tot)103-107
Aantal pagina's5
TijdschriftCancer Genetics and Cytogenetics
Volume95
Nummer van het tijdschrift1
DOI's
StatusGepubliceerd - mei 1997
Extern gepubliceerdJa

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