TY - JOUR
T1 - Cytogenetic study of a nodular hyperplasia of the thyroid after irradiation for Hodgkin's disease
AU - van den Berg, Eva
AU - van Doormaal, Jasper J.
AU - Oosterhuis, J. Wolter
AU - de Jong, Bauke
AU - Buist, Janneke
AU - Vos, Anne Marie
AU - Dam, Anke
AU - Vermeij, Albert
PY - 1991/5
Y1 - 1991/5
N2 - We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.
AB - We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.
UR - http://www.scopus.com/inward/record.url?scp=0025794213&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(91)90110-G
DO - 10.1016/0165-4608(91)90110-G
M3 - Article
C2 - 2036636
AN - SCOPUS:0025794213
SN - 0165-4608
VL - 53
SP - 15
EP - 21
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -