TY - JOUR
T1 - Cytogenetics as a tool in the histologic subclassification of chondrosarcomas
AU - Dijkhuizen, Trijnie
AU - van den Berg, Eva
AU - Molenaar, Willemina M.
AU - Oosterhuis, J. Wolter
AU - Dam, Anke
AU - Wiersema, Janneke
AU - Schraffordt Koops, Heimen
AU - de Jong, Bauke
PY - 1994/9
Y1 - 1994/9
N2 - Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.
AB - Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.
UR - http://www.scopus.com/inward/record.url?scp=0028127312&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(94)90457-X
DO - 10.1016/0165-4608(94)90457-X
M3 - Article
C2 - 7923056
AN - SCOPUS:0028127312
SN - 0165-4608
VL - 76
SP - 100
EP - 105
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 2
ER -