Samenvatting
The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 ×) and the chromosomes #1(3 ×), #3(3 ×), #7(4 ×), #8(4 ×), and #14(2 ×). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome #7 and loss or abnormalities of chromosomes #8 and #14.
| Originele taal-2 | Engels |
|---|---|
| Pagina's (van-tot) | 53-61 |
| Aantal pagina's | 9 |
| Tijdschrift | Cancer Genetics and Cytogenetics |
| Volume | 30 |
| Nummer van het tijdschrift | 1 |
| DOI's | |
| Status | Gepubliceerd - jan. 1988 |
| Extern gepubliceerd | Ja |
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