TY - JOUR
T1 - Cytogenetics of carcinoma in situ of the testis
AU - Vos, Anne Marie
AU - Oosterhuis, J. Wolter
AU - de Jong, Bauke
AU - Buist, Janneke
AU - Koops, Heimen Schraffordt
PY - 1990/5
Y1 - 1990/5
N2 - Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.
AB - Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.
UR - http://www.scopus.com/inward/record.url?scp=0025330183&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(90)90011-X
DO - 10.1016/0165-4608(90)90011-X
M3 - Article
C2 - 2331686
AN - SCOPUS:0025330183
SN - 0165-4608
VL - 46
SP - 75
EP - 81
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -