Defective iron homeostasis in β2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man

Keyphrases

• Knock-in Mouse Model 100%
• β2-microglobulin (β2-MG) 100%
• Hereditary Hemochromatosis 100%
• Iron Homeostasis 100%
• Hemachromatosis 100%
• Liver 66%
• Iron Metabolism 66%
• Reconstitution 33%
• Hematopoietic Cells 33%
• I.Family 33%
• Pathologic 33%
• MHC Class II 33%
• Gene Products 33%
• Mutant Mice 33%
• Novel Genes 33%
• Mucosal Cells 33%
• Kupffer Cells 33%
• Parenchymal Cells 33%
• Iron Deposition 33%
• Hepatic Iron Overload 33%
• Gut mucosa 33%
• Functional Support 33%
• Mucosal Defects 33%
• Transferrin Saturation 33%

Biochemistry, Genetics and Molecular Biology

• Knockout Mouse 100%
• Iron Metabolism 100%
• Iron Homeostasis 100%
• Microglobulin 100%
• Mouse Mutant 50%
• Mucosa 50%
• Major Histocompatibility Complex 50%
• Gene Product 50%
• Kupffer Cell 50%
• Iron Poisoning 50%
• Iron Overload 50%
• Transferrin Saturation 50%
• Hematopoietic Cell 50%
• Blood Plasma 50%