Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma

Keyphrases

• Neuroblastoma 100%
• MUTYH 100%
• Repair Pathway 100%
• 8-oxoguanine 100%
• OGG1 100%
• Copy number Variation 50%
• Tumor Evolution 33%
• Neuroblastoma Cells 16%
• Tumor 16%
• Whole Genome Sequencing 16%
• Childhood Brain Tumors 16%
• Mutagenesis 16%
• Mutational Signatures 16%
• Neuroblastoma Tumor 16%
• Poor Survival 16%
• Tumor Organoids 16%
• Signature Analysis 16%
• Whole-genome Sequence Data 16%
• Organoid Models 16%
• CRISPR/Cas9 Genome Editing 16%
• Cytosine 16%
• Clone Groups 16%
• DNA Glycosylase 16%
• Sequencing Data Analysis 16%
• Induction Treatment 16%
• Clustering Analysis 16%

Immunology and Microbiology

• Whole Genome Sequencing 100%
• Mutagenesis 50%
• Wild Type 50%
• Organoid 50%
• Gene Editing 50%
• CRISPR/Cas9 50%
• Neuroblastoma Cell 50%

Biochemistry, Genetics and Molecular Biology

• Guanine 100%
• Cytosine 16%