Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss

Keyphrases

• Bone Loss 100%
• Age-dependent 100%
• Calcium Binding 100%
• Matricellular Proteins 100%
• Bone Healing 100%
• SMOC2 100%
• SPARC 100%
• Mouse Model 40%
• Tooth Injuries 40%
• GFP Reporter 40%
• Germ Cells 20%
• Loss Function 20%
• Wound Healing 20%
• Whole Genome 20%
• RNA-seq Analysis 20%
• Extracellular Matrix Protein 1 (ECM1) 20%
• Skeletal Malformations 20%
• Bone Resorption 20%
• Days of Treatment 20%
• Phosphoprotein 20%
• Oligodontia 20%
• Homozygous mutant 20%
• Osteonecrosis 20%
• Enamel Matrix 20%
• 2-blocks 20%
• Number of Teeth 20%
• Matrix metalloprotease-9 20%
• Maxillary Teeth 20%
• Microdontia 20%
• Periodontal Bone Loss 20%
• Odontogenic Ameloblast-associated Protein 20%
• Periodontal Tissue 20%
• Tooth Avulsion 20%
• Craniofacial Development 20%
• Tooth Size 20%
• Root Loss 20%
• Dentin Dysplasia 20%
• Regenerative Repair 20%
• Osteoclast Activity 20%
• Enamel Prisms 20%
• Avulsion Fracture 20%
• Cyclooxygenase-2 Inhibitors 20%
• Dentin Matrix 20%
• Jawbone 20%
• Tooth Root 20%
• Matrix Components 20%
• Reporter Expression 20%
• Alveolar Bone 20%
• Hypoplasia 20%

Medicine and Dentistry

• Osteolysis 100%
• Osteonectin 100%
• Calcium Binding 100%
• Dental Trauma 60%
• RNA Sequence 20%
• Body Weight 20%
• Injury 20%
• Extracellular Matrix 20%
• Hypoplasia 20%
• Ibuprofen 20%
• Bone Necrosis 20%
• Wound Healing 20%
• Genomic RNA 20%
• Skeleton Malformation 20%
• Jaw 20%
• Metalloproteinase 20%
• Dentinogenesis Imperfecta 20%
• Cyclooxygenase 2 Inhibitor 20%
• Alveolar Bone 20%
• Tooth Root 20%
• Periodontium 20%
• Dentin Matrix Protein 1 20%
• Avulsion Injury 20%
• Oligodontia 20%
• Osteoclast Activity 20%
• Craniofacial Development 20%
• Tooth Size 20%
• Tooth Number 20%
• Microdontia 20%
• Ameloblast 20%
• Germ Cell 20%