Diabetes from growth hormone excess

Sebastian J. Neggers, Aart J. Van Der Lely

Onderzoeksoutput: Hoofdstuk in Boek/Rapport/CongresprocedureHoofdstukpeer review

2 Citaten (Scopus)


This chapter tries to address the fascinating interplay between the glucose-insulin system and the growth hormone (GH)-insulin-like growth factor 1 system from the angle of GH excess. As these two systems are so closely linked, one might expect that when GH secretion is pathologically increased, the glucose-insulin system must adapt to this - and indeed it does. In acromegaly, diabetes - or at least impaired glucose tolerance - is the result of GH excess. The medical treatment modalities for acromegaly have interesting and diverse effects on glycemic control. As many of these aspects are also important for the discernment of the metabolic differences between type 1 and type 2 diabetes mellitus, we believe that the reader might obtain a better understanding of the (patho)physiology of the link between glycemic control and GH secretion.

Originele taal-2Engels
TitelDiabetes Secondary to Endocrine and Pancreatic Disorders
UitgeverijS. Karger AG
Aantal pagina's9
ISBN van elektronische versie9783318025989
ISBN van geprinte versie9783318025972
StatusGepubliceerd - 10 apr. 2014
Extern gepubliceerdJa

Publicatie series

NaamFrontiers in Diabetes
ISSN van geprinte versie0251-5342
ISSN van elektronische versie1662-2995


Duik in de onderzoeksthema's van 'Diabetes from growth hormone excess'. Samen vormen ze een unieke vingerafdruk.

Citeer dit