EANM-EORTC general recommendations for sentinel node diagnostics in melanoma

Annette H. Chakera, Birger Hesse, Zeynep Burak, James R. Ballinger, Allan Britten, Corrado Caracò, Alistair J. Cochran, Martin G. Cook, Krzysztof T. Drzewiecki, Richard Essner, Einat Even-Sapir, Alexander M.M. Eggermont, Tanja Gmeiner Stopar, Christian Ingvar, Martin C. Mihm, Stanley W. McCarthy, Nicola Mozzillo, Omgo E. Nieweg, Richard A. Scolyer, Hans StarzJohn F. Thompson, Giuseppe Trifirò, Giuseppe Viale, Sergi Vidal-Sicart, Roger Uren, Wendy Waddington, Arturo Chiti, Alain Spatz, Alessandro Testori

Onderzoeksoutput: Bijdrage aan tijdschriftArtikel recenserenpeer review

158 Citaten (Scopus)


The accurate diagnosis of a sentinel node in melanoma includes a sequence of procedures from different medical specialities (nuclear medicine, surgery, oncology, and pathology). The items covered are presented in 11 sections and a reference list: (1) definition of a sentinel node, (2) clinical indications, (3) radiopharmaceuticals and activity injected, (4) dosimetry, (5) injection technique, (6) image acquisition and interpretation, (7) report and display, (8) use of dye, (9) gamma probe detection, (10) surgical techniques in sentinel node biopsy, and (11) pathological evaluation of melanoma-draining sentinel lymph nodes. If specific recommendations given cannot be based on evidence from original, scientific studies, referral is given to "general consensus" and similar expressions. The recommendations are designed to assist in the practice of referral to, performance, interpretation and reporting of all steps of the sentinel node procedure in the hope of setting state-of-the-art standards for good-quality evaluation of possible spread to the lymphatic system in intermediate-to-high risk melanoma without clinical signs of dissemination.

Originele taal-2Engels
Pagina's (van-tot)1713-1742
Aantal pagina's30
TijdschriftEuropean Journal of Nuclear Medicine and Molecular Imaging
Nummer van het tijdschrift10
StatusGepubliceerd - 2009
Extern gepubliceerdJa


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