Een vaginale zwelling en bloedverlies bij een peuter

N Pleunis, W B Breunis, J H M Merks, A E Bouwma, J W van der Steeg

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review


BACKGROUND: The differential diagnosis of vaginal blood loss in childhood is broad, and includes irritation of the mucous membranes, trauma, tumours, foreign bodies and sexual abuse. Physical and additional examination is often initially difficult; however, prompt detection of a rhabdomyosarcoma, a soft-tissue tumour principally diagnosed in childhood, is vitally important.

CASE DESCRIPTION: A 3-year-old girl with a history of vaginal blood loss and an introital mass was referred to the gynaecologist. Treatment with oestriol and triamcinolone cream did not lead to healing. Pathological examination of a biopsy taken under general anaesthetic indicated an embryonic rhabdomyosarcoma. Chemotherapy, surgical resection and brachytherapy lead to persistent remission of the tumour.

CONCLUSION: Because rhabdomyosarcoma is rare and can present atypically, diagnosis can be delayed. Early recognition is, however, essential and this condition should be placed high in the differential diagnosis by vaginal blood loss or vaginal abnormality in childhood.

Vertaalde titel van de bijdrageA toddler with a vaginal mass and blood loss; the rhabdomyosarcoma
Originele taal-2Nederlands
Pagina's (van-tot)D1674
TijdschriftNederlands tijdschrift voor geneeskunde
StatusGepubliceerd - 2017
Extern gepubliceerdJa


  • Biopsy
  • Brachytherapy
  • Child, Preschool
  • Female
  • Humans
  • Rhabdomyosarcoma/diagnosis
  • Uterine Hemorrhage/diagnosis


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