Emotional distress in 652 dutch very long-term survivors of childhood cancer, using the hospital anxiety and depression scale (HADS)

Ivana M.M. Van Der Geest, Wendy Van Dorp, Wim C.J. Hop, Sebastian J.C.M.M. Neggers, Andrica C.H. De Vries, Rob Pieters, Femke K. Aarsen, Marry M. Van Den Heuvel-Eibrink

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

25 Citaten (Scopus)

Samenvatting

BACKGROUND:: After a more successful treatment of pediatric cancer, the number of childhood cancer survivors is progressively increasing. Consequently, awareness of psychological late sequelae is important. PROCEDURE:: The Hospital Anxiety and Depression Scale (HADS) was used as a screening tool for emotional distress in a single center cohort of 652 childhood cancer survivors (median age 23 y [range, 15 to 46 y], median follow-up time 15 y [range, 5 to 42 y]). Results were compared with a control group of 440 Dutch subjects. A higher HADS score linearly reflect a higher level of emotional distress, and a score ≥15 is indicative of clinically significant emotional distress. RESULTS:: Mean HADS score of the childhood cancer survivors was not different from the control group (P=0.38). Survivors exposed to global central nervous system (CNS) irradiation had a significantly higher HADS score than the control group (8.3±6.6; P=0.05) as well as other survivors (P=0.01). Forty-three survivors (7%) had a HADS score ≥15. Survivors with a HADS score ≥15 were variously spread over the diagnostic-related and treatment-related subgroups. Linear regression analysis showed that high educational achievement (β=-1.28; P<0.01) and age at the time of the study (β=0.08; P=0.03) were both significantly associated with the HADS score. CONCLUSIONS:: Emotional distress does not occur more often in childhood cancer survivors than in the normal population. No disease-related or treatment-related variable was independently associated with emotional distress.

Originele taal-2Engels
Pagina's (van-tot)525-529
Aantal pagina's5
TijdschriftJournal of Pediatric Hematology/Oncology
Volume35
Nummer van het tijdschrift7
DOI's
StatusGepubliceerd - okt. 2013
Extern gepubliceerdJa

Vingerafdruk

Duik in de onderzoeksthema's van 'Emotional distress in 652 dutch very long-term survivors of childhood cancer, using the hospital anxiety and depression scale (HADS)'. Samen vormen ze een unieke vingerafdruk.

Citeer dit