Engineering large-scale chromosomal deletions by CRISPR-Cas9

Keyphrases

• Cas9 Protein 100%
• Chromosomal Deletion 100%
• Large Deletion 100%
• Tumor Subtype 50%
• Tumor Growth 25%
• Neuroblastoma Cell Line 25%
• Tumor Development 25%
• Type-specific 25%
• Cell Line Models 25%
• Intermittent Region 25%
• Chromosome 11q 25%
• Functional Genomics 25%
• Approaches to Study 25%
• Chromosome 6q 25%
• Colony Forming Capacity 25%
• Double-strand Breaks 25%
• Defining Characteristic 25%
• Genomic Approaches 25%
• Driving Capacity 25%
• Isogenic Cell Lines 25%
• Oncogenic Drivers 25%
• Subtype-specific 25%
• Isogenic Model 25%
• Recurrency 25%
• Therapeutic Potential 25%
• Effective Techniques 25%

Biochemistry, Genetics and Molecular Biology

• CRISPR/Cas9 100%
• Chromosome 11q 50%
• Functional Genomics 50%
• Colony Forming Unit S 50%
• Chromosome 6q 50%
• Growth, Development and Aging 50%