Samenvatting
The European pediatric Soft tissue sarcoma Study Group analyzed all children with epithelioid hemangioendothelioma prospectively registered in the NRSTS-05 (EUDRACT 2005-001139-31) and in MTS-2008 (NCT00379457) studies: 10 patients with localized and one with metastatic disease. Median age was 14.3 years (range, 9.0-18.8). Local therapy was initial primary surgery in seven cases, and five patients received systemic therapy. No patients received radiotherapy. After a median follow-up of 50 months (range, 6-176) for living patients, nine patients remain alive off therapy and two died. Five-year progression free and overall survivals are, respectively, 77.1% (95% confidence interval [CI]: 34.5-93.9) and 74.1% (95% CI: 28.1-93.0).
Originele taal-2 | Engels |
---|---|
Pagina's (van-tot) | e29882 |
Tijdschrift | Pediatric blood & cancer |
Volume | 69 |
Nummer van het tijdschrift | 10 |
Vroegere onlinedatum | 16 jul. 2022 |
DOI's | |
Status | Gepubliceerd - okt. 2022 |
Trefwoorden
- children
- hemangioendothelioma
- soft tissue sarcoma
- surgery