TY - JOUR
T1 - Expansion of the Candidozyma haemuli Species Complex - The Novel Species Candidozyma molenica, Isolated from Clinical and Environmental Sources
AU - Zandijk, Annemarie
AU - van der Bruggen, Tjomme
AU - Sipiczki, Matthias
AU - Tissing, Wim J.E.
AU - Wolfs, Tom F.W.
AU - Gerrits van den Ende, Bert
AU - Groenewald, Marizeth
AU - Hagen, Ferry
N1 - © 2025. The Author(s).
PY - 2025/9/1
Y1 - 2025/9/1
N2 - Due to the recent unprecedented global rise of Candidozyma auris in hospital environments the members of the Candidozyma haemuli species complex have raised significant interest of clinicians and researchers. Until the finding of C. auris, the species complex did not receive much attention as the known pathogenic species were only rarely encountered in hospitals and clinical diagnostic laboratories. During the past years several new species were described, such as Candidozyma khanbhai and Candidozyma vulturna, that were found to be of clinical importance. Here, we used phylogenetic and phenotypic analyses –including antifungal susceptibility testing– to characterize and describe a new and potentially clinically relevant yeast that we obtained from clinical specimen and flowers, representing the proposed novel species Candidozyma molenica.
AB - Due to the recent unprecedented global rise of Candidozyma auris in hospital environments the members of the Candidozyma haemuli species complex have raised significant interest of clinicians and researchers. Until the finding of C. auris, the species complex did not receive much attention as the known pathogenic species were only rarely encountered in hospitals and clinical diagnostic laboratories. During the past years several new species were described, such as Candidozyma khanbhai and Candidozyma vulturna, that were found to be of clinical importance. Here, we used phylogenetic and phenotypic analyses –including antifungal susceptibility testing– to characterize and describe a new and potentially clinically relevant yeast that we obtained from clinical specimen and flowers, representing the proposed novel species Candidozyma molenica.
KW - Candidozyma auris
KW - Candidozyma haemuli species complex
KW - Candidozyma khanbhai
KW - Candidozyma vulturna
KW - Emerging pathogen
KW - Misidentification
KW - Humans
KW - Phylogeny
KW - Flowers/microbiology
KW - DNA, Ribosomal/genetics
KW - Sequence Analysis, DNA
KW - Microbial Sensitivity Tests
KW - Antifungal Agents/pharmacology
KW - Environmental Microbiology
KW - DNA, Fungal/genetics
KW - DNA, Ribosomal Spacer/genetics
KW - Cluster Analysis
KW - Mycoses/microbiology
UR - https://www.scopus.com/pages/publications/105014944531
UR - https://www.mendeley.com/catalogue/977bfef0-6cb3-335d-9a07-b4d02c0dc34d/
U2 - 10.1007/s11046-025-00985-z
DO - 10.1007/s11046-025-00985-z
M3 - Article
C2 - 40888982
AN - SCOPUS:105014944531
SN - 0301-486X
VL - 190
JO - Mycopathologia
JF - Mycopathologia
IS - 5
M1 - 81
ER -