Expression profiler: Next generation - An online platform for analysis of microarray data

Misha Kapushesky, Patrick Kemmeren, Aedín C. Culhane, Steffen Durinck, Jan Ihmels, Christine Körner, Meelis Kull, Aurora Torrente, Ugis Sarkans, Jaak Vilo, Alvis Brazma

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

107 Citaten (Scopus)

Samenvatting

Expression Profiler (EP, http://www.ebi.ac.uk/expressionprofiler) is a web-based platform for microarray gene expression and other functional genomics-related data analysis. The new architecture, Expression Profiler: next generation (EP:NG), modularizes the original design and allows individual analysis-task-related components to be developed by different groups and yet still seamlessly to work together and share the same user interface look and feel. Data analysis components for gene expression data preprocessing, missing value imputation, filtering, clustering methods, visualization, significant gene finding, between group analysis and other statistical components are available from the EBI (European Bioinformatics Institute) web site. The web-based design of Expression Profiler supports data sharing and collaborative analysis in a secure environment. Developed tools are integrated with the microarray gene expression database ArrayExpress and form the exploratory analytical front-end to those data. EP:NG is an open-source project, encouraging broad distribution and further extensions from the scientific community.

Originele taal-2Engels
Pagina's (van-tot)W465-W470
TijdschriftNucleic Acids Research
Volume32
Nummer van het tijdschriftWEB SERVER ISS.
DOI's
StatusGepubliceerd - 1 jul. 2004
Extern gepubliceerdJa

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