Favorable outcome of neonatal cerebrospinal fluid shunt-associated Candida meningitis with caspofungin

Jop Jans, Roger J.M. Brüggemann, V. Christdmann, Paul E. Verweij, Adilia Warris

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

10 Citaten (Scopus)

Samenvatting

Invasive Candida infections associated with medical devices are very difficult to cure without device removal. We present a case of neonatal cerebrospinal fluid shunt-associated Candida meningitis, in which removal of the device was precluded, that was successfully treated with caspofungin. Pharmacokinetic assessment of caspofungin concentrations in cerebrospinal fluid showed that exposure was adequate in the presence of a high systemic exposure. In complex cases of neonatal Candida infections involving medical devices, the addition of caspofungin might be beneficial.

Originele taal-2Engels
Pagina's (van-tot)2391-2393
Aantal pagina's3
TijdschriftAntimicrobial Agents and Chemotherapy
Volume57
Nummer van het tijdschrift5
DOI's
StatusGepubliceerd - mei 2013
Extern gepubliceerdJa

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