Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

Keyphrases

• Allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) 100%
• Fludarabine 100%
• Outcome Prediction 100%
• Confidence Interval 50%
• Hazard Ratio 50%
• Non-relapse Mortality 30%
• Event-free Survival 20%
• Graft Failure 20%
• Hematopoietic Cell Transplantation 20%
• Clinical Outcomes 10%
• Pharmacokinetic Analysis 10%
• Therapeutic Drug Monitoring 10%
• Body Surface Area 10%
• Conditioning Regimen 10%
• Area-based 10%
• Busulfan 10%
• Exposure Outcome 10%
• Strong Predictor 10%
• Population Pharmacokinetic Model 10%
• Individualized Dosing 10%
• Immune Reconstitution 10%
• Antithymocyte Globulin 10%
• Mortality Hazard 10%
• Survival Prediction 10%
• Area under the Concentration-time Curve 10%
• Renal Function 10%
• Malignant Disorders 10%
• Time-to-event Model 10%
• Myeloablative Conditioning 10%
• Weight Function 10%
• Group Events 10%
• Overexposed 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Fludarabine 100%
• Event Free Survival 20%
• Graft Failure 20%
• Pharmacokinetics 20%
• Disease 10%
• Therapeutic Drug Monitoring 10%
• Pharmacodynamics 10%
• Busulfan 10%
• Thymocyte Antibody 10%