Frequent germ-line succinate dehydrogenase subunit D gene mutations in patients with apparently sporadic parasympathetic paraganglioma

Keyphrases

• Germ Cells 100%
• Gene mutation 100%
• Paraganglioma 100%
• Succinate Dehydrogenase Subunit D 100%
• Tumor 40%
• Germline mutation 30%
• Family History 20%
• Familial Paraganglioma 20%
• Molecular Characteristics 10%
• Netherlands 10%
• Number of Patients 10%
• Somatic mutation 10%
• Clinical Characteristics 10%
• Personal History 10%
• Genetic Testing 10%
• Missense mutation 10%
• Erasmus 10%
• Rotterdam 10%
• Tumor DNA 10%
• Clinical Management 10%
• Unselected Patients 10%
• Gel Electrophoresis 10%
• Highly Conserved Regions 10%
• Sequence Determination 10%
• Sporadic Form 10%

Biochemistry, Genetics and Molecular Biology

• Gene Mutation 100%
• Germ Cell 100%
• Succinate Dehydrogenase 100%
• Fumarate Reductase 100%
• Germline Mutation 30%
• Somatic Mutation 10%
• Allele 10%
• Prevalence 10%
• Genetic Screening 10%
• Missense Mutation 10%
• Conformation 10%
• Shotgun Sequencing 10%
• Gel Electrophoresis 10%

Neuroscience

• Gene Mutation 100%
• Germ Cell 100%
• Succinate Dehydrogenase 100%
• Fumarate Reductase 100%
• Somatics 30%
• Missense Mutation 10%
• Shotgun Sequencing 10%
• Gel Electrophoresis 10%