TY - GEN
T1 - Frequent itemsets for genomic profiling
AU - De Graaf, Jeannette M.
AU - De Menezes, Renée X.
AU - Boer, Judith M.
AU - Kosters, Walter A.
PY - 2005
Y1 - 2005
N2 - Frequent itemset mining is a promising approach to the study of genomic profiling data. Here a dataset consists of real numbers describing the relative level in which a clone occurs in human DNA for given patient samples. One can then mine, for example, for sets of samples that share some common behavior on the clones, i.e., gains or losses. Frequent itemsets show promising biological expressiveness, can be computed efficiently, and are very flexible. Their visualization provides the biologist with useful information for the discovery of patterns. Also it turns out that the use of (larger) frequent itemsets tends to filter out noise.
AB - Frequent itemset mining is a promising approach to the study of genomic profiling data. Here a dataset consists of real numbers describing the relative level in which a clone occurs in human DNA for given patient samples. One can then mine, for example, for sets of samples that share some common behavior on the clones, i.e., gains or losses. Frequent itemsets show promising biological expressiveness, can be computed efficiently, and are very flexible. Their visualization provides the biologist with useful information for the discovery of patterns. Also it turns out that the use of (larger) frequent itemsets tends to filter out noise.
UR - http://www.scopus.com/inward/record.url?scp=33646201321&partnerID=8YFLogxK
U2 - 10.1007/11560500_10
DO - 10.1007/11560500_10
M3 - Conference contribution
AN - SCOPUS:33646201321
SN - 3540291040
SN - 9783540291046
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 104
EP - 116
BT - Computational Life Sciences - First International Symposium, CompLife 2005, Proceedings
PB - Springer Verlag
T2 - 1st International Symposium on Computational Life Sciences, CompLife 2005
Y2 - 25 September 2005 through 27 September 2005
ER -