Genome stability, progressive kidney failure and aging

Hannes Lans; Jan H.J. Hoeijmakers

doi:10.1038/ng.2363

Genome stability, progressive kidney failure and aging

Hannes Lans, Jan H.J. Hoeijmakers

Onderzoeksoutput: Bijdrage aan tijdschrift › Artikel › peer review

24 Citaten (Scopus)

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Two new studies report mutations in FAN1 and three other genome-stability genes that tie the DNA damage response to progressive kidney failure and the dysfunction of several other organs. These findings provide clues to the underlying causes of tissue decline and may add a series of genes to the growing list of genome maintenance factors that protect against premature aging.

Originele taal-2	Engels
Pagina's (van-tot)	836-838
Aantal pagina's	3
Tijdschrift	Nature Genetics
Volume	44
Nummer van het tijdschrift	8
DOI's	https://doi.org/10.1038/ng.2363
Status	Gepubliceerd - aug. 2012
Extern gepubliceerd	Ja

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10.1038/ng.2363

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Genome stability, progressive kidney failure and aging

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