Health-related quality of life and psychosocial functioning of adolescents with inflammatory bowel disease

Mariike De Boer, Martha Grootenhuis, Bert Derkx, Bob Last

Onderzoeksoutput: Bijdrage aan tijdschriftArtikelpeer review

88 Citaten (Scopus)


Background: This study aimed to study how inflammatory bowel disease (IBD) affects health-related quality of life (HRQoL) during adolescence and to examine how self-esteem influences HRQoL. Methods: We compared self-esteem, anxiety, and parental reports on behavioral problems in a group of IBD patients to a healthy norm group. Forty children and 38 parents filled out questionnaires separately. Trait anxiety, self-perception, and the data on the Child Behavior Checklist were taken to compare the IBD population with healthy norms, using Student's t tests and 1-sample t tests. Effect sizes were calculated to show the clinical relevance of the differences. Multiple regression analyses were performed to assess the association between disease-related variables and self-perception with HRQoL, anxiety, and problem behavior. Results: The results of this study show that adolescents with IBD, especially boys, have a significantly worse HRQoL and show more internalizing problem behavior compared with healthy peers. An important predictor of HRQoL is self-esteem. Conclusions: In conclusion, adolescents with IBD are at risk for experiencing problems with their illness. Because self-esteem is an important predictor of HRQoL, it should be taken into account in future interventions for these children.

Originele taal-2Engels
Pagina's (van-tot)400-406
Aantal pagina's7
TijdschriftInflammatory Bowel Diseases
Nummer van het tijdschrift4
StatusGepubliceerd - apr. 2005
Extern gepubliceerdJa


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