High-performance liquid chromatographic determination of stabilized 4-hydroxyifosfamide in human plasma and erythrocytes

Keyphrases

• Human Plasma 100%
• Reversed-phase HPLC 100%
• Semicarbazide 100%
• High-performance Liquid Chromatographic 100%
• Human Erythrocytes 100%
• Chromatographic Determination 100%
• Ifosfamide 50%
• Limit of Quantification 50%
• Pharmacokinetic Study 50%
• Sample Pretreatment 50%
• Liquid-liquid Extraction 50%
• Validation Studies 50%
• Between-day 50%
• Potassium 50%
• Clinically Relevant Concentrations 50%
• Acetonitrile 50%
• Continuous Infusion 50%
• Erythrocytes 50%
• Buffer pH 50%
• Within-day 50%
• Optimization Study 50%
• Stability Study 50%
• Dihydrogen Phosphate 50%
• Derivatization 50%
• UV Detection 50%
• Mobile Phase 50%
• Triethylamine 50%
• Conventional Dose 50%
• C8 Column 50%
• Ethyl Acetate 50%
• Biological Matrices 50%

Chemistry

• High-Pressure Liquid Chromatography 100%
• Semicarbazide 100%
• 4-Hydroxyifosfamide 100%
• Acetonitrile 50%
• Pharmacokinetics 50%
• Metabolite 50%
• Buffer Solution 50%
• Ethyl Acetate 50%
• Derivatization 50%
• K 50%
• Ifosfamide 50%
• Triethylamine 50%
• Mobile Phase Composition 50%
• Dihydrogenphosphate 50%
• stability 50%
• Solvent Extraction 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Semicarbazide 100%
• Reverse Phase High Performance Liquid Chromatography 100%
• Ifosfamide 50%
• Acetonitrile 50%
• Buffer 50%
• Isotopes of Potassium 50%
• Acetic Acid Ethyl Ester 50%
• Triethylamine 50%
• Pharmacokinetics 50%